Prevalence of Pediatric Functional Gastrointestinal Disorders Utilizing the Rome IV Criteria

1Canlas A, 2van Tilburg M, 3Shulman R
1William Carey University, Hattiesburg, MS, USA; 2University of North Carolina, Buies Creek, North caro, USA; 3Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA

OBJECTIVE: The new pediatric Rome IV criteria have established changes to the criteria for Functional Gastrointestinal Disorders (FGIDs). The goal of the current study is to assess the prevalence of FGIDs in children 0-18 years old according to the Rome IV diagnostic criteria as reported by parents in a representative community sample.

STUDY DESIGN: Mothers (n=1255) of children aged 0-18 years old in the US were recruited to complete an online survey about their child's gastrointestinal symptoms, quality of life, and other health conditions.

RESULTS: Based on the Rome IV criteria, 24.7% of infants and toddlers aged 0-3 years and 25.0% of children and adolescents aged 4-18 years fulfilled symptom-based criteria for an FGID. The most common FGID were infant regurgitation among infants (24.1%), and functional constipation among both toddlers (18.5%) and children and adolescents (14.1%). Quality of life was diminished in pediatric patients with FGIDs (Median= 71.69 vs. Median=87.60; z=-11.41; p<0.001). Children were more likely to qualify for an FGID if their parent qualified for an FGID (35.4% vs. 23.0%; p<0.001).

CONCLUSION: This is the first study to report the prevalence of pediatric FGIDs based on Rome IV criteria. FGIDs are common in pediatric populations of all ages and are associated with decreased quality of life. These data are of importance to treatment and research of FGIDs.